Manchester United will kick off their 2025/26 Premier League campaign with a high-stakes clash against Arsenal at Old Trafford on August 17. Under new manager Ruben Amorim, the Red Devils face a challenging start, with trips to Fulham and Manchester City and a home game against Chelsea all packed into their opening six fixtures.
Without the distraction of European football, United are expected to concentrate fully on improving after what was their worst Premier League season to date. The early-season Manchester Derby (Sept 13) and a fierce showdown with Liverpool at Anfield (Oct 18) mark key dates for fans.
Amorim’s side will host City on January 17 and Liverpool on May 2 in what could be crucial fixtures late in the season.
Other notable matches include Tottenham (Nov 8 & Feb 7), Chelsea (Sept 20 & Apr 18), and a final-day trip to Brighton on May 24.
United’s full focus on domestic competition could give them a strategic advantage, but the early fixture congestion will provide an immediate test of their resilience and squad depth.

